NEURAL PROTOCOL Rx

       Date _______________________

Dr. Grace Ziem, M.D., P.H. Patient name___________________________________________________ 16926 Eyler’s Valley Rd. Address________________________________________________________ Emmitsburg, MD 21727 Phone_________________________________________________________ Ph: 301-241-4346, Fax 301-241-4348 Date of birth____________________________________________________

Medically Necessary Protocol

   I. Reduced L-Glutathione

• Nebulized Soln: 10mg/ml  20mg/ml  30mg/ml  60mg/ml  100mg/ml   AeronebGo
• Disp: 120ml  240ml     extra dropper    saline   sterile water   Refill _____ times   PRN
• Begin ____ DROPS, 2 droppers water. As inflammation calms, gradually dilute less. Goal 2 ml via nebulizer 2-4 times daily.

   II. Nitric Oxide Scavenger

• Hydroxocobalamine at _____mg/drop.
• Dilute 1 drop in ____drops water, add to dropers (ml) water in nebulizer.  Use 2-4 times daily.                                 Add to nebulizer AFTER adding 2 droppers (ml) water/saline.  Use 2-4 times daily.                                               Nasal nipple   extra 4cc brown bottle   extra nasal spray bottle   Disp  ___ml   amt per pt  Refill PRN
• Nasal hydroxocobalamine at ____ mcg/spray. One spray each nostril __ daily __ with exposures or with reactions, one spray per nostril every few seconds until symptoms better. Dilute if any irritation. Disp. ___ ml Refill PRN

  III. Neural Sensitization Capsules:

       Always take with food in stomach. Begin gradually, take three times daily or more for best protection with meals/snack.             Ultimate E, One daily   lipoic separate NSP with lipoic   Refill PRN

• Glutathione Function/Reactivation:

         1. Ascorbic acid (Vitamin C) 2000mg (2gm) per day. Patient self testing Perque C strips: 800-806-8671. PRN                               Buffered C ____gm BID, _____ TID with exposures.   Refill PRN

         2. Selenium, 400mcg/day as selenomethione (bioactive form)

         3. Alpha lipoic acid, 600mg/day. Begin at 100mg/day. Take separately WITH FOOD (e.g. Jarrow/Thorne                                         and increase gradually until full dose tolerated). Reduce dose if gastric irritation.

         4. Riboflavin-5-phosphate (bioactive form): 100mg/day

• Components of superoxide dismutase:

         5. Zinc, 20mg/day as picolinate (or more if deficient on SpectraCell testing)

         6. Copper, 1mg/day, as picolinate (or more if deficient on SpectraCell testing)

         7. Manganese, 2mg/day, as picolinate

• Compounds related to peroxynitrite biochemistry:

         8. Magnesium, 400mg per day, as magnesium malate (or more if deficient on RBC mineral testing).

         9. Betaine (also called trimethylglycine) (methyl donor), 500mg/day.

       10. Bioactive folate (MTHF) 1 mg/d

• Scavengers of peroxynitrite and its breakdown products:

       11. Thorne Ultimate E 500IU or Xymogen Xcellent E with 200IU gamma tocopherol (peroxynitrite scavenger). 1 capsule                   daily.

       12. Ginkgo biloba extract, 120mg per day

       13. Silymarin (milk thistle extract) 200mg per day

       14. Bilberry extract, 150mg per day

       15. Cranberry extract, 400mg per day

       16. Carotenoid mixture (5mg lycopene, 5mg beta-carotene, 5mg lutein, smaller amounts of other carotenoids per day)

• Superoxide Scavenger:

       17. Activin grape seed proanthocyanidin 300mg/day

       18. Epigallocatechin gallate (EGCG) 300 mg

• GABA formation to calm NMDA activation

       19. Pyridoxal-5-phosphate (bioactive form) 100mg/day

       20. Taurine 500mg – 1 to 4 taken separately mid to late evening

• Energy metabolism for protocol healing and calming NMDA

 21. Acetyl-L-carnitine 500mg/day

22. Niacinamide 50mg

23. Thiamine HCL 50mg

24. CoQ-10 100mg/day

25. Molybdenum 200mcg

26. Chromium 200mcg

27. Pantethine (B5)500mg

28. Biotin 1mg

 Scientific Botancials Folarinse use in 5:2mg ratio with B12

 Xymogen CoQ Max^CF

• Membrane/myelin/brain and nerve repair

 Carlso/Nordic Naturals cod liver oil 1 Tbs/day

 Phosphaline Xymogen up to 1-2 Tbs/day

 Carlson tocotrienols 1-2/day

• Other
• Rx    
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• THIS Rx WITH ALL COMPONENTS MUST BE TAKEN FREQUENTLY EACH DAY TO INTERRUPT THE VICIOUS BIOCHEMICAL CYCLE OF NEURAL SENSITIZATION. For questions on ingredient purity/efficacy, contact, Key Pharmacy, 800-878-1322. Follow Dr. Ziem’s step-by-step instructions and call promptly for questions/problems..

   _______________________________________________________________________________

   073007  Dr. Grace Ziem, M.D., Dr. P.H. (Medicare Provider No. 9546)

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